Abstract :The advances in laser technology have led to many new devices and uses. Lasers have been used to treat onychomycosis, but this technology is in its infancy. Laser therapy for the temporary cosmetic improvement of onychomycosis of toenails received FDA approval in 2010. We report a patient treating onychomycosis of the fingernails using the Genesis Plus laser. The advantages are the simplicity of the procedure, no concern for systemic (drug) reactions or contraindications, and the efficacy of the procedure. The disadvantages include cost, the necessity for individualization of settings with clinical analysis of nail involvement and thickness, and slight warmth or heat during the procedure. We feel this modality provides a great service to dermatologic patients, especially those with co-morbidities, and dermatologists should be aware of this use.